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C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301593100

C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

About this item

Full title

C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1897-1902

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mincle (also called as Clec4e and Clecsf9) is a C-type lectin receptor expressed in activated phagocytes. Recently, we have demonstrated that Mincle is an FcRγ-associated activating receptor that senses damaged cells. To search an exogenous ligand(s), we screened pathogenic fungi using cell line expressing Mincle, FcRγ, and NFAT-GFP reporter. We fo...

Alternative Titles

Full title

C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201301593100

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301593100

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0805177106

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