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Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney tra...

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney tra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301602378

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation

About this item

Full title

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3390-3395

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

While studies in animal models have linked Toll-like receptor (TLR) 4 signaling to kidney injury induced by ischemia and reperfusion, the relevance of TLR4 activation to allograft injury in human kidney transplants is unknown. Here we show that TLR4 is constitutively expressed within all donor kidneys but is significantly higher in deceased-, compa...

Alternative Titles

Full title

Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201301602378

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301602378

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0810169106

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