Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the...
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Fli-1 and Erg are closely related members of the Ets family of transcription factors. Both genes are translocated in human cancers, including Ewing's sarcoma, leukemia, and in the case of Erg, more than half of all prostate cancers. Although evidence from mice and humans suggests that Fli-1 is required for megakaryopoiesis, and that Erg is required...
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Full title
Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage
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TN_cdi_fao_agris_US201301669094
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301669094
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0906556106
