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SAH domain extends the functional length of the myosin lever

SAH domain extends the functional length of the myosin lever

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301720483

SAH domain extends the functional length of the myosin lever

About this item

Full title

SAH domain extends the functional length of the myosin lever

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (52), p.22193-22198

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Stable, single alpha-helix (SAH) domains are widely distributed in the proteome, including in myosins, but their functions are unknown. To test whether SAH domains can act as levers, we replaced four of the six calmodulin-binding IQ motifs in the levers of mouse myosin 5a (Myo5) with the putative SAH domain of Dictyostelium myosin MyoM of similar l...

Alternative Titles

Full title

SAH domain extends the functional length of the myosin lever

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201301720483

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301720483

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0909851106

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