Tumor-infiltrating NY-ESO-1-specific CD8⁺ T cells are negatively regulated by LAG-3 and PD-1 in huma...
Tumor-infiltrating NY-ESO-1-specific CD8⁺ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
NY-ESO-1 is a "cancer-testis" antigen frequently expressed in epithelial ovarian cancer (EOC) and is among the most immunogenic tumor antigens defined to date. In an effort to understand in vivo tolerance mechanisms, we assessed the phenotype and function of NY-ESO-1-specific CD8⁺ T cells derived from peripheral blood lymphocytes (PBLs), tumor-infi...
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Full title
Tumor-infiltrating NY-ESO-1-specific CD8⁺ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
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TN_cdi_fao_agris_US201301834690
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301834690
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1003345107
