Establishment of HIV-1 latency in resting CD4⁺ T cells depends on chemokine-induced changes in the a...
Establishment of HIV-1 latency in resting CD4⁺ T cells depends on chemokine-induced changes in the actin cytoskeleton
About this item
Full title
Author / Creator
Cameron, Paul U , Saleh, Suha , Sallmann, Georgina , Solomon, Ajantha , Wightman, Fiona , Evans, Vanessa A , Boucher, Genevieve , Haddad, Elias K , Sekaly, Rafick-Pierre , Harman, Andrew N , Anderson, Jenny L , Jones, Kate L , Mak, Johnson , Cunningham, Anthony L , Jaworowski, Anthony and Lewin, Sharon R
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Eradication of HIV-1 with highly active antiretroviral therapy (HAART) is not possible due to the persistence of long-lived, latently infected resting memory CD4⁺ T cells. We now show that HIV-1 latency can be established in resting CD4⁺ T cells infected with HIV-1 after exposure to ligands for CCR7 (CCL19), CXCR3 (CXCL9 and CXCL10), and CCR6 (CCL2...
Alternative Titles
Full title
Establishment of HIV-1 latency in resting CD4⁺ T cells depends on chemokine-induced changes in the actin cytoskeleton
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_fao_agris_US201301894675
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201301894675
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1002894107
