Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes
Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Hephaestin (Heph), a membrane-bound multicopper ferroxidase (FOX) expressed in duodenal enterocytes, is required for optimal iron absorption. However, sex-linked anemia (sla) mice harboring a 194-amino acid deletion in the Heph protein are able to absorb dietary iron despite reduced expression and mislocalization of the mutant protein. Thus Heph ma...
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Full title
Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes
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TN_cdi_fao_agris_US201400180778
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201400180778
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1120833109
