Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoie...
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The Ten-Eleven-Translocation 2 (TET2) gene encodes a member of TET family enzymes that alters the epigenetic status of DNA by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Somatic loss-of-function mutations of TET2 are frequently observed in patients with diverse myeloid malignancies, including myelodysplastic syndromes, myeloprolif...
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Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
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TN_cdi_fao_agris_US201400182916
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201400182916
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1112317108
