Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Activated macrophages are described as classically activated or M1 type and alternatively activated or M2 type, depending on their response to proinflammatory stimuli and the expression of genetic markers including iNOS, arginase1, Ym1, and Fizz1. Here we report that Akt kinases differentially contribute to macrophage polarization, with Akt1 ablati...
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Full title
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
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TN_cdi_fao_agris_US201600128705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600128705
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1119038109