N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
In the course of apoptosis, activated caspases cleave ∼500 to ∼1,000 different proteins in a mammalian cell. The dynamics of apoptosis involve a number of previously identified, caspase-generated proapoptotic protein fragments, defined as those that increase the probability of apoptosis. In contrast to activated caspases, which can be counteracted...
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Full title
N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments
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Record Identifier
TN_cdi_fao_agris_US201600128978
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600128978
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1207786109
