Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves...
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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MicroRNAs are dysregulated in a setting of heart disease and have emerged as promising therapeutic targets. MicroRNA-34 family members (miR-34a, -34b, and -34c) are up-regulated in the heart in response to stress. In this study, we assessed whether inhibition of the miR-34 family using an s.c.-delivered seed-targeting 8-mer locked nucleic acid (LNA...
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Full title
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
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TN_cdi_fao_agris_US201600130074
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600130074
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1206432109
