Ca²⁺/calmodulin-dependent protein kinase kinase β phosphorylation of Sirtuin 1 in endothelium is ath...
Ca²⁺/calmodulin-dependent protein kinase kinase β phosphorylation of Sirtuin 1 in endothelium is atheroprotective
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Author / Creator
Wen, Liang , Chen, Zhen , Zhang, Fan , Cui, Xiaopei , Sun, Wei , Geary, Greg G , Wang, Yinsheng , Johnson, David A , Zhu, Yi , Chien, Shu and Shyy, John Y-J
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Atheroprotective flow exerts antioxidative and anti-inflammatory effects on vascular endothelial cells (ECs), in part through the induction of Sirtuin 1 (SIRT1), a class III histone deacetylase. The role of Ca ²⁺/calmodulin-dependent protein kinase kinase (CaMKK)β in flow induction of SIRT1 both in vitro and in vivo was investigated. Pulsatile shea...
Alternative Titles
Full title
Ca²⁺/calmodulin-dependent protein kinase kinase β phosphorylation of Sirtuin 1 in endothelium is atheroprotective
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Record Identifier
TN_cdi_fao_agris_US201600137702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600137702
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1309354110
