Coevolutionary signals across protein lineages help capture multiple protein conformations
Coevolutionary signals across protein lineages help capture multiple protein conformations
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
A long-standing problem in molecular biology is the determination of a complete functional conformational landscape of proteins. This includes not only proteins’ native structures, but also all their respective functional states, including functionally important intermediates. Here, we reveal a signature of functionally important states in several...
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Full title
Coevolutionary signals across protein lineages help capture multiple protein conformations
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TN_cdi_fao_agris_US201600140725
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600140725
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1315625110
