βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells
βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Identified over a dozen years ago in the brain and pancreatic islet, β IV-spectrin is critical for the local organization of protein complexes throughout the nervous system. β IV-Spectrin targets ion channels and adapter proteins to axon initial segments and nodes of Ranvier in neurons, and β IV-spectrin dysfunction underlies ataxia and early death...
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Full title
βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells
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TN_cdi_fao_agris_US201600140967
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600140967
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1314195110
