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Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600141927

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

About this item

Full title

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13588-13593

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Chronic immune activation is a major complication of antiretroviral therapy (ART) for HIV infection and can cause a devastating immune reconstitution inflammatory syndrome (IRIS) in the brain. The mechanism of T-cell activation in this population is not well understood. We found HIV-Tat protein and IL-17–expressing mononuclear cells in the brain of...

Alternative Titles

Full title

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201600141927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600141927

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1308673110

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