Differential role of nonhomologous end joining factors in the generation, DNA damage response, and m...
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
About this item
Full title
Author / Creator
Felgentreff, Kerstin , Du, Likun , Weinacht, Katja G. , Dobbs, Kerry , Bartish, Margarita , Giliani, Silvia , Schlaeger, Thorsten , DeVine, Alexander , Schambach, Axel , Woodbine, Lisa J. , Davies, Graham , Baxi, Sachin N. , van der Burg, Mirjam , Bleesing, Jack , Gennery, Andrew , Manis, John , Pan-Hammarström, Qiang and Notarangelo, Luigi D.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Nonhomologous end-joining (NHEJ) is a key pathway for efficient repair of DNA double-strand breaks (DSBs) and V(D)J recombination. NHEJ defects in humans cause immunodeficiency and increased cellular sensitivity to ionizing irradiation (IR) and are variably associated with growth retardation, microcephaly, and neurodevelopmental delay. Repair of DN...
Alternative Titles
Full title
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
Authors, Artists and Contributors
Author / Creator
Du, Likun
Weinacht, Katja G.
Dobbs, Kerry
Bartish, Margarita
Giliani, Silvia
Schlaeger, Thorsten
DeVine, Alexander
Schambach, Axel
Woodbine, Lisa J.
Davies, Graham
Baxi, Sachin N.
van der Burg, Mirjam
Bleesing, Jack
Gennery, Andrew
Manis, John
Pan-Hammarström, Qiang
Notarangelo, Luigi D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_fao_agris_US201600144352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600144352
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1323649111
