Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-spe...
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Neural stem cells (NSCs) generate new granule cells throughout life in the mammalian hippocampus. Canonical Wnt signaling regulates the differentiation of NSCs towards the neuronal lineage. Here we identified the prospero-related homeodomain transcription factor Prox1 as a target of β-catenin-TCF/LEF signaling in vitro and in vivo. Prox1 overexpre...
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Full title
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis
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TN_cdi_fao_agris_US201600192352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201600192352
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1013456108
