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Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_healthsolutions_A689285626

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t

About this item

Full title

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t

Publisher

Nature Publishing Group

Journal title

Leukemia, 2017-06, Vol.31 (6), p.1278

Language

English

Formats

Publication information

Publisher

Nature Publishing Group

Subjects

More information

Scope and Contents

Contents

Core-binding factor acute myeloid leukemia (CBF-AML) is defined by the presence of either t(8;21)(q22;q22)/RUNX1-RUNX1T1 or inv(16)(p13.1q22)/t(16;16)(p13.1;q22)/CBFB-MYH11. The resulting fusion genes require a 'second hit' to initiate leukemogenesis. Mutation assessment of 177 adults with CBF-AML, including 68 with t(8;21) and 109 with inv(16)/t(1...

Alternative Titles

Full title

Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_healthsolutions_A689285626

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_healthsolutions_A689285626

Other Identifiers

ISSN

0887-6924

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