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Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol tr...

Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol tr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISN_A613716539

Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol trisphosphate-mediated intracellular calcium homeostasis

About this item

Full title

Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol trisphosphate-mediated intracellular calcium homeostasis

Publisher

Canada: NRC Research Press

Journal title

Genome, 2020-02, Vol.63 (2), p.61-90

Language

English

Formats

Publication information

Publisher

Canada: NRC Research Press

More information

Scope and Contents

Contents

Nucleobindin-1 is an EF-hand calcium-binding protein with a distinctive profile, predominantly localized to the Golgi in insect and wide-ranging vertebrate cell types, alike. Its putative involvements in intracellular calcium (Ca
2+
) homeostasis have never been phenotypically characterized in any model organism. We have analyzed an adult-via...

Alternative Titles

Full title

Genetic analyses uncover pleiotropic compensatory roles for Drosophila Nucleobindin-1 in inositol trisphosphate-mediated intracellular calcium homeostasis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_incontextgauss_ISN_A613716539

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISN_A613716539

Other Identifiers

ISSN

0831-2796

E-ISSN

1480-3321

DOI

10.1139/gen-2019-0113

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