Differential Responses of Human Regulatory T Cells
Differential Responses of Human Regulatory T Cells
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Publisher
Public Library of Science
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Language
English
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Publisher
Public Library of Science
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Contents
The immunosuppressive drug rapamycin (RAPA) promotes the expansion of CD4.sup.+ CD25.sup.high Foxp3.sup.+ regulatory T cells via mechanisms that remain unknown. Here, we studied expansion, IL-2R-[gamma] chain signaling, survival pathways and resistance to apoptosis in human Treg responding to RAPA. CD4.sup.+ CD25.sup.+ and CD4.sup.+ CD25.sup.neg T...
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Full title
Differential Responses of Human Regulatory T Cells
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TN_cdi_gale_incontextgauss_ISR_A473048327
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A473048327
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005994
