Tacrolimus
Tacrolimus
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Publisher
Public Library of Science
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Language
English
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Publisher
Public Library of Science
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Scope and Contents
Contents
Tacrolimus (FK506) is a widely used immunosuppressive drug. Its effects on hepatic fibrosis have been controversial and attributed to immunosuppression. We show that in vitro FK506, inhibited synthesis of type I collagen polypeptides, without affecting expression of collagen mRNAs. In vivo, administration of FK506 at a dose of 4 mg/kg completely pr...
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Full title
Tacrolimus
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_gale_incontextgauss_ISR_A478436241
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A478436241
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0065897