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Tacrolimus

Tacrolimus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A478436241

Tacrolimus

About this item

Full title

Tacrolimus

Publisher

Public Library of Science

Journal title

PloS one, 2013-06, Vol.8 (6), p.e65897

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Tacrolimus (FK506) is a widely used immunosuppressive drug. Its effects on hepatic fibrosis have been controversial and attributed to immunosuppression. We show that in vitro FK506, inhibited synthesis of type I collagen polypeptides, without affecting expression of collagen mRNAs. In vivo, administration of FK506 at a dose of 4 mg/kg completely pr...

Alternative Titles

Full title

Tacrolimus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_incontextgauss_ISR_A478436241

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A478436241

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0065897

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