The DNA binding domain and the C-terminal region of DNA Ligase IV specify its role in V
The DNA binding domain and the C-terminal region of DNA Ligase IV specify its role in V
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Public Library of Science
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Language
English
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Public Library of Science
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DNA Ligase IV is responsible for the repair of DNA double-strand breaks (DSB), including DSBs that are generated during V(D)J recombination. Like other DNA ligases, Ligase IV contains a catalytic core with three subdomains-the DNA binding (DBD), the nucleotidyltransferase (NTD), and the oligonucleotide/oligosaccharide-fold subdomain (OBD). Ligase I...
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Full title
The DNA binding domain and the C-terminal region of DNA Ligase IV specify its role in V
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TN_cdi_gale_incontextgauss_ISR_A738478496
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_incontextgauss_ISR_A738478496
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0282236
