Do electrospray mass spectra reflect the ligand binding state of proteins in solution?
Do electrospray mass spectra reflect the ligand binding state of proteins in solution?
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Publisher
Ottawa, Canada: NRC Research Press
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Language
English
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Publisher
Ottawa, Canada: NRC Research Press
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Contents
Electrospray ionization (ESI) mass spectrometry (MS) has become a popular tool for monitoring ligandprotein and proteinprotein interactions. Due to the "gentle" nature of the ionization process, it is often possible to transfer weakly bound complexes into the gas phase, thus making them amenable to MS detection. One problem with this technique is...
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Full title
Do electrospray mass spectra reflect the ligand binding state of proteins in solution?
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TN_cdi_gale_infotracacademiconefile_A145680534
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A145680534
Other Identifiers
ISSN
0008-4042
E-ISSN
1480-3291
DOI
10.1139/v05-194
