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Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early...

Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A195070414

Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates

About this item

Full title

Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates

Publisher

Public Library of Science

Journal title

PLoS genetics, 2009-01, Vol.5 (1)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

In many mammalian neurons, dense clusters of ion channels at the axonal initial segment and nodes of Ranvier underlie action potential generation and rapid conduction. Axonal clustering of mammalian voltage-gated sodium and KCNQ (Kv7) potassium channels is based on linkage to the actin-spectrin cytoskeleton, which is mediated by the adaptor protein...

Alternative Titles

Full title

Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates

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Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A195070414

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A195070414

Other Identifiers

ISSN

1553-7390

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