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Citreorosein inhibits degranulation and leukotriene [C.sub.4] generation through suppression of Syk...

Citreorosein inhibits degranulation and leukotriene [C.sub.4] generation through suppression of Syk...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A359411069

Citreorosein inhibits degranulation and leukotriene [C.sub.4] generation through suppression of Syk pathway in mast cells

About this item

Full title

Citreorosein inhibits degranulation and leukotriene [C.sub.4] generation through suppression of Syk pathway in mast cells

Publisher

Springer

Journal title

Molecular and cellular biochemistry, 2012-06, Vol.365 (1-2), p.333

Language

English

Formats

Publication information

Publisher

Springer

Subjects

Subjects and topics

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Scope and Contents

Contents

The aim of this study was to evaluate whether citreorosein (CIT), a naturally occurring anthraquinone isolated from Polygoni cuspidati (P. cuspidati) radix, modulates degranulation and 5-lipoxygenase (5-LO)-dependent leukotriene [C.sub.4] ([LTC.sub.4]) generation in mast cells. Cit suppresses both degranulation and the generation of [LTC.sub.4] in...

Alternative Titles

Full title

Citreorosein inhibits degranulation and leukotriene [C.sub.4] generation through suppression of Syk pathway in mast cells

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Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A359411069

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A359411069

Other Identifiers

ISSN

0300-8177

DOI

10.1007/s11010-012-1273-3

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