Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21[sup.high] Cells In Vivo
Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21[sup.high] Cells In Vivo
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Author / Creator
Yi, Zimei , Ren, Le , Wei, Yu , Chen, Siyi , Zhao, Jiechen , Zhu, Jiayu and Wu, Junhua
Publisher
MDPI AG
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Language
English
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MDPI AG
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P21 and p16 have been identified as inducers of senescence. Many transgenic mouse models have been developed to target cells expressing high levels of p16Ink4a (p16[sup.high]) and investigate their potential contribution to tissue dysfunction in aging, obesity, and other pathological conditions. However, the specific roles of p21 in various senesce...
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Full title
Generation of a p21 Reporter Mouse and Its Use to Identify and Eliminate p21[sup.high] Cells In Vivo
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TN_cdi_gale_infotracacademiconefile_A751926642
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A751926642
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ISSN
1422-0067
DOI
10.3390/ijms24065565
