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IIn Silico/I Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domai...

IIn Silico/I Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A762477512

IIn Silico/I Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domain of PARP-1 Protein

About this item

Full title

IIn Silico/I Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domain of PARP-1 Protein

Publisher

MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2023-08, Vol.13 (8)

Language

English

Formats

Publication information

Publisher

MDPI AG

More information

Scope and Contents

Contents

The molecular toxicity of the uranyl ion (UO[sub.2] [sup.2+] ) in living cells is primarily determined by its high affinity to both native and potential metal-binding sites that commonly occur in the structure of biomolecules. Recent advances in computational and experimental research have shed light on the structural properties and functional impa...

Alternative Titles

Full title

IIn Silico/I Simulations Reveal Molecular Mechanism of Uranyl Ion Toxicity towards DNA-Binding Domain of PARP-1 Protein

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracacademiconefile_A762477512

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A762477512

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom13081269

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