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Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A109959047

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

About this item

Full title

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2003-10, Vol.302 (5644), p.453-457

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The formation of an atherosclerotic lesion is mediated by lipid-laden macrophages (foam cells), which also establish chronic inflammation associated with lesion progression. The peroxisome proliferator-activated receptor (PPAR) γ promotes lipid uptake and efflux in these atherogenic cells. In contrast we found that the closely related receptor PPAR...

Alternative Titles

Full title

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracgeneralonefile_A109959047

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A109959047

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1087344

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