IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9
IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The Toll-like receptor (TLR) family has important roles in microbial recognition and dendritic cell activation
1
,
2
. TLRs 7 and 9 can recognize nucleic acids
3
,
4
,
5
,
6
and trigger signalling cascades that activate plasmacytoid dendritic cells to produce interferon-α (IFN-α) (refs
7
,
8
). TLR7/9...
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Full title
IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9
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TN_cdi_gale_infotracgeneralonefile_A185452072
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A185452072
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature04641