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IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A185452072

IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

About this item

Full title

IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2006-04, Vol.440 (7086), p.949-953

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Toll-like receptor (TLR) family has important roles in microbial recognition and dendritic cell activation
1
,
2
. TLRs 7 and 9 can recognize nucleic acids
3
,
4
,
5
,
6
and trigger signalling cascades that activate plasmacytoid dendritic cells to produce interferon-α (IFN-α) (refs
7
,
8
). TLR7/9...

Alternative Titles

Full title

IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracgeneralonefile_A185452072

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A185452072

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature04641

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