HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Countering ischaemia
The transcriptional regulator PGC-1α mediates many of the effects of exercise on skeletal muscle, including mitochondrial biogenesis and fibre-type switching. Now this protein has been found to activate a natural defence pathway that protects ischaemic tissues. PGC-1α is produced in response to hypoxia and nutrient deprivati...
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Full title
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
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TN_cdi_gale_infotracgeneralonefile_A189748394
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A189748394
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature06613
