Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation
Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Expression of somatostatin in the brain declines during aging in various mammals including apes and humans
1
,
2
. A prominent decrease in this neuropeptide also represents a pathological characteristic of Alzheimer disease
3
,
4
. Using
in vitro
and
in vivo
paradigms, we show that somatostatin regulates the meta...
Alternative Titles
Full title
Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation
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TN_cdi_gale_infotracgeneralonefile_A192626821
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A192626821
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1206
