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Dopaminergic Loss and Inclusion Body Formation in [Alpha]-Synuclein Mice: Implications for Neurodege...

Dopaminergic Loss and Inclusion Body Formation in [Alpha]-Synuclein Mice: Implications for Neurodege...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A60053299

Dopaminergic Loss and Inclusion Body Formation in [Alpha]-Synuclein Mice: Implications for Neurodegenerative Disorders

About this item

Full title

Dopaminergic Loss and Inclusion Body Formation in [Alpha]-Synuclein Mice: Implications for Neurodegenerative Disorders

Publisher

American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2000-02, Vol.287 (5456), p.1265-1265

Language

English

Formats

Publication information

Publisher

American Association for the Advancement of Science

More information

Scope and Contents

Contents

To elucidate the role of the synaptic protein a-synuclein in neurodegenerative disorders, transgenic mice expressing wild-type human [Alpha]-synuclein were generated. Neuronal expression of human [Alpha]-synuclein resulted in progressive accumulation of [Alpha]-synuclein--and ubiquitin-immunoreactive inclusions in neurons in the neocortex, hippocam...

Alternative Titles

Full title

Dopaminergic Loss and Inclusion Body Formation in [Alpha]-Synuclein Mice: Implications for Neurodegenerative Disorders

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracgeneralonefile_A60053299

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A60053299

Other Identifiers

ISSN

0036-8075

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