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Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mic...

Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A678805083

Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice

About this item

Full title

Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2021-10, Vol.99 (10), p.1000-1006

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

The Hippo/YAP (yes-associated protein) pathway is an important signaling pathway to control organ development and tissue homeostasis. YAP is a downstream effector of the Hippo pathway and a critical mediator of mechanic stress. Hypertensive nephropathy is characterized with glomerular sclerosis stiffness and renal fibrosis. The present study invest...

Alternative Titles

Full title

Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracgeneralonefile_A678805083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracgeneralonefile_A678805083

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/cjpp-2021-0033

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