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p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A181819742

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

About this item

Full title

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2007-06, Vol.39 (6), p.741-749

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The mitogen-activated protein kinase (MAPK) p38α controls inflammatory responses and cell proliferation. Using mice carrying conditional
Mapk14
(also known as
p38α
) alleles, we investigated its function in postnatal development and tumorigenesis. When we specifically deleted
Mapk14
in the mouse embryo, fetuses developed to term b...

Alternative Titles

Full title

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A181819742

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A181819742

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng2033

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