Effect of Gender on the Tolerability, Safety and Pharmacokinetics of Clazosentan Following Long-Term...
Effect of Gender on the Tolerability, Safety and Pharmacokinetics of Clazosentan Following Long-Term Infusion
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Publisher
New Zealand: Wolters Kluwer Health, Inc
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Language
English
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Publisher
New Zealand: Wolters Kluwer Health, Inc
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The purpose of this study was to investigate the effect of gender on the tolerability, safety and pharmacokinetics of clazosentan, an intravenous endothelin receptor antagonist.
Clazosentan was infused at a dosage of 0.05 mg/kg/h or 0.1 mg/kg/h for 72 hours in 8 female and 8 male healthy volunteers, respectively. Tolerability and safety were ass...
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Full title
Effect of Gender on the Tolerability, Safety and Pharmacokinetics of Clazosentan Following Long-Term Infusion
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TN_cdi_gale_infotracmisc_A199858490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A199858490
Other Identifiers
ISSN
1173-2563
DOI
10.2165/00044011-200727110-00006
