Defective survival of naive CD[8.sup.+] T lymphocytes in the absence of the β3 regulatory subunit of...
Defective survival of naive CD[8.sup.+] T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels
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Nature Publishing Group
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English
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Nature Publishing Group
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The survival of T lymphocytes requires sustained, [Ca.sup.2+] influx-dependent gene expression. The molecular mechanism that governs sustained [Ca.sup.2+] influx in naive T lymphocytes is unknown. Here we report an essential role for the (33 regulatory subunit of voltage-gated calcium ([C.sub.v]) channels in the maintenance of naive [CD8.sup.+] T c...
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Defective survival of naive CD[8.sup.+] T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels
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TN_cdi_gale_infotracmisc_A213084313
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A213084313
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1529-2908
DOI
10.1038/ni.1793