Perforin expression directly ex vivo by HIV-specific [CD8.sup.+] T-cells is a correlate of HIV elite...
Perforin expression directly ex vivo by HIV-specific [CD8.sup.+] T-cells is a correlate of HIV elite control
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Author / Creator
Hersperger, Adam R , Pereyra, Florencia , Nason, Martha , Demers, Korey , Sheth, Prameet , Shin, Lucy Y , Kovacs, Colin M , Rodriguez, Benigno , Sieg, Scott F , Teixeira-Johnson, Leia , Gudonis, Debbie , Goepfert, Paul A , Lederman, Michael M , Frank, Ian , Makedonas, George , Kaul, Rupert , Walker, Bruce D and Betts, Michael R
Publisher
Public Library of Science
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Language
English
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Publisher
Public Library of Science
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Contents
Many immune correlates of [CD8.sup.+] T-cell-mediated control of HIV replication, including polyfunctionality, proliferative ability, and inhibitory receptor expression, have been discovered. However, no functional correlates using ex vivo cells have been identified with the known ability to cause the direct elimination of HIV-infected cells. We ha...
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Full title
Perforin expression directly ex vivo by HIV-specific [CD8.sup.+] T-cells is a correlate of HIV elite control
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TN_cdi_gale_infotracmisc_A228434911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A228434911
Other Identifiers
ISSN
1553-7366
DOI
10.1371/journal.ppat.1000917
