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9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A249463620

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

About this item

Full title

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2011-02, Vol.470 (7333), p.264-268

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Heart disease link to inflammatory signalling
A non-coding region on chromosome 9p21 was previously shown to associate with coronary artery disease and type 2 diabetes, and the region has been implicated in regulating neighbouring genes. Here the authors identify 33 distinct enhancers within this region and show that single nucleotide polymorphi...

Alternative Titles

Full title

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A249463620

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A249463620

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09753

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