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Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole: Monitoring of Intralum...

Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole: Monitoring of Intralum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A269920505

Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole: Monitoring of Intraluminal and Plasma Drug Concentrations

About this item

Full title

Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole: Monitoring of Intraluminal and Plasma Drug Concentrations

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2011-11, Vol.50 (11), p.725-734

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background and Objective:
Posaconazole (Noxafil®) is an extended-spectrum triazole antifungal agent for prevention and treatment of invasive fungal infections. An inadequate dietary intake and abnormal gastric pH levels are common in critically ill patients receiving antifungal treatment with posaconazole, resulting in unpredictable bioavailabil...

Alternative Titles

Full title

Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole: Monitoring of Intraluminal and Plasma Drug Concentrations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A269920505

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A269920505

Other Identifiers

ISSN

0312-5963

E-ISSN

1179-1926

DOI

10.2165/11592630-000000000-00000

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