Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-in...
Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals
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Publisher
American Society for Clinical Investigation
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Language
English
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Publisher
American Society for Clinical Investigation
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Scope and Contents
Contents
Depletion of CD[4.sup.+] T cells from the gut occurs rapidly during acute HIV-1 infection. This has been linked to systemic inflammation and disease progression as a result of translocation of microbial products from the gut lumen into the bloodstream. Combined antiretroviral therapy (cART) substantially restores CD[4.sup.+] T cell numbers in perip...
Alternative Titles
Full title
Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals
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Record Identifier
TN_cdi_gale_infotracmisc_A276438392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A276438392
Other Identifiers
ISSN
0021-9738
DOI
10.1172/JCI59011.