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Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-in...

Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A276438392

Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

About this item

Full title

Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

Publisher

American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2012-01, Vol.122 (1), p.62

Language

English

Formats

Publication information

Publisher

American Society for Clinical Investigation

More information

Scope and Contents

Contents

Depletion of CD[4.sup.+] T cells from the gut occurs rapidly during acute HIV-1 infection. This has been linked to systemic inflammation and disease progression as a result of translocation of microbial products from the gut lumen into the bloodstream. Combined antiretroviral therapy (cART) substantially restores CD[4.sup.+] T cell numbers in perip...

Alternative Titles

Full title

Altered CD[4.sup.+] T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A276438392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A276438392

Other Identifiers

ISSN

0021-9738

DOI

10.1172/JCI59011.

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