Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
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Nature Publishing Group
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English
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Nature Publishing Group
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Aneuploidy--the state of having uneven numbers of chromosomes--is a hallmark of cancer (1) and a feature identified in yeast from diverse habitats (2-5). Recent studies have shown that aneuploidy is a form of large-effect mutation that is able to confer adaptive phenotypes under diverse stress conditions (2,6). Here we investigate whether pleiotrop...
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Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
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TN_cdi_gale_infotracmisc_A280717708
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A280717708
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0028-0836
E-ISSN
1476-4687
DOI
10.1038/naturel0795
