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Altered responsiveness to TGF-[beta] results in reduced PAPSS2 expression and alterations in the bio...

Altered responsiveness to TGF-[beta] results in reduced PAPSS2 expression and alterations in the bio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A284576501

Altered responsiveness to TGF-[beta] results in reduced PAPSS2 expression and alterations in the biomechanical properties of mouse articular cartilage

About this item

Full title

Altered responsiveness to TGF-[beta] results in reduced PAPSS2 expression and alterations in the biomechanical properties of mouse articular cartilage

Publisher

BioMed Central Ltd

Journal title

Arthritis research & therapy, 2012-03, Vol.14, p.R49

Language

English

Formats

Publication information

Publisher

BioMed Central Ltd

More information

Scope and Contents

Contents

Introduction Previous studies have indicated that transforming growth factor [beta] (TGF-[beta]) signaling has a critical role in cartilage homeostasis and repair, yet the mechanisms of TGF-[beta]'s chondroprotective effects are not known. Our objective in this study was to identify downstream targets of TGF-[beta] that could act to maintain bioche...

Alternative Titles

Full title

Altered responsiveness to TGF-[beta] results in reduced PAPSS2 expression and alterations in the biomechanical properties of mouse articular cartilage

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A284576501

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A284576501

Other Identifiers

ISSN

1478-6354

DOI

10.1186/ar3762

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