Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Type I interferons regulate immune responses by signaling via heterodimeric IFNAR1-IFNAR2 complexes. Hertzog and colleagues reveal a unique IFN-β–IFNAR1 signaling complex that is IFNAR2-independent and modulates expression of a distinct set of interferon-inducible genes.
Type I interferons are important in regulating immune responses to pathogen...
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Full title
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
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TN_cdi_gale_infotracmisc_A344154640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A344154640
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2667
