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Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy...

Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A354859232

Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment

About this item

Full title

Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

Cell and tissue research, 2010-02, Vol.339 (2), p.397-410

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

To probe pro-fibrotic mechanisms in dystrophic muscle, we isolated primary fibroblasts from Duchenne muscular dystrophy (DMD) and control muscle biopsies and induced transdifferentiation in myofibroblasts by transforming growth factor β1 (TGF-β1) treatment. We compared proliferating activity, soluble collagen production, and transcript and protein...

Alternative Titles

Full title

Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A354859232

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A354859232

Other Identifiers

ISSN

0302-766X

E-ISSN

1432-0878

DOI

10.1007/s00441-009-0889-4

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