Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy...
Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Scope and Contents
Contents
To probe pro-fibrotic mechanisms in dystrophic muscle, we isolated primary fibroblasts from Duchenne muscular dystrophy (DMD) and control muscle biopsies and induced transdifferentiation in myofibroblasts by transforming growth factor β1 (TGF-β1) treatment. We compared proliferating activity, soluble collagen production, and transcript and protein...
Alternative Titles
Full title
Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment
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Author / Creator
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Record Identifier
TN_cdi_gale_infotracmisc_A354859232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A354859232
Other Identifiers
ISSN
0302-766X
E-ISSN
1432-0878
DOI
10.1007/s00441-009-0889-4