Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface...
Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin
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Public Library of Science
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English
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Public Library of Science
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Ceruloplasmin is a ferroxidase that interacts with ferroportin to export cellular iron, but is not expressed in neurons. We recently reported that the amyloid precursor protein (APP) is the analogous iron-exporting chaperone for neurons and other cells. The ferroxidase activity of APP has since been called into question. Using a triplex Fe.sup.2+ o...
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Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin
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TN_cdi_gale_infotracmisc_A416778483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A416778483
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0114174
