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1,25-Dihydroxyvitamin D.sub.3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T...

1,25-Dihydroxyvitamin D.sub.3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A416975832

1,25-Dihydroxyvitamin D.sub.3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

About this item

Full title

1,25-Dihydroxyvitamin D.sub.3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

Publisher

Public Library of Science

Journal title

PloS one, 2014-10, Vol.9 (10)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

The emergence of regulatory T cells (Tregs) as central mediators of peripheral tolerance in the immune system has led to an important area of clinical investigation to target these cells for the treatment of autoimmune diseases such as type 1 diabetes. We have demonstrated earlier that in vitro treatment of T cells from healthy individuals with TX5...

Alternative Titles

Full title

1,25-Dihydroxyvitamin D.sub.3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A416975832

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A416975832

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0109194

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