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Key Role of the Endothelial TGF-[beta]/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmona...

Key Role of the Endothelial TGF-[beta]/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmona...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A418127606

Key Role of the Endothelial TGF-[beta]/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension

About this item

Full title

Key Role of the Endothelial TGF-[beta]/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension

Publisher

Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Mutations affecting transforming growth factor-beta (TGF-[beta]) superfamily receptors, activin receptor-like kinase (ALK)-1, and endoglin (ENG) occur in patients with pulmonary arterial hypertension (PAH). To determine whether the TGF-[beta]/ALK1/ENG pathway was involved in PAH, we investigated pulmonary TGF-[beta], ALK1, ALK5, and ENG expressions...

Alternative Titles

Full title

Key Role of the Endothelial TGF-[beta]/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A418127606

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A418127606

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0100310

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