Human Papillomavirus 16 Oncoprotein E7 Stimulates UBF1-Mediated rDNA Gene Transcription, Inhibiting...
Human Papillomavirus 16 Oncoprotein E7 Stimulates UBF1-Mediated rDNA Gene Transcription, Inhibiting a p53-Independent Activity of p14.sup.ARF
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Public Library of Science
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English
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Public Library of Science
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High-risk human papillomavirus oncoproteins E6 and E7 play a major role in HPV-related cancers. One of the main functions of E7 is the degradation of pRb, while E6 promotes the degradation of p53, inactivating the p14.sup.ARF -p53 pathway. pRb and p14.sup.ARF can repress ribosomal DNA (rDNA) transcription in part by targeting the Upstream Binding F...
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Full title
Human Papillomavirus 16 Oncoprotein E7 Stimulates UBF1-Mediated rDNA Gene Transcription, Inhibiting a p53-Independent Activity of p14.sup.ARF
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TN_cdi_gale_infotracmisc_A418707693
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A418707693
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0096136
