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Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through E...

Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through E...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A418707865

Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through ET.sub.A Receptor

About this item

Full title

Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through ET.sub.A Receptor

Publisher

Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

The endothelin axis, comprising endothelins (ET-1, ET-2 and ET-3) and their receptors (ET.sub.A R and ET.sub.B R), has emerged as relevant player in tumor growth and metastasis. Here, we investigated the involvement of ET-1/ET.sub.A R axis in chronic lymphocytic leukemia (CLL). CLL cells expressed higher levels of ET-1 and ET.sub.A receptor as comp...

Alternative Titles

Full title

Endothelin-1 Promotes Survival and Chemoresistance in Chronic Lymphocytic Leukemia B Cells through ET.sub.A Receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A418707865

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A418707865

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0098818

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