Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Ca...
Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb.sup.sl Mutations by Quantitative Trait Locus Analysis
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Public Library of Science
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English
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Public Library of Science
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Hirschsprung's disease (HSCR) is a congenital disease in neonates characterized by the absence of the enteric ganglia in a variable length of the distal colon. This disease results from multiple genetic interactions that modulate the ability of enteric neural crest cells to populate developing gut. We previously reported that three rat strains with...
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Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb.sup.sl Mutations by Quantitative Trait Locus Analysis
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TN_cdi_gale_infotracmisc_A423858996
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A423858996
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0122068