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Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Ca...

Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Ca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A423858996

Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb.sup.sl Mutations by Quantitative Trait Locus Analysis

About this item

Full title

Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb.sup.sl Mutations by Quantitative Trait Locus Analysis

Publisher

Public Library of Science

Journal title

PloS one, 2015-03, Vol.10 (3)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

Hirschsprung's disease (HSCR) is a congenital disease in neonates characterized by the absence of the enteric ganglia in a variable length of the distal colon. This disease results from multiple genetic interactions that modulate the ability of enteric neural crest cells to populate developing gut. We previously reported that three rat strains with...

Alternative Titles

Full title

Identification of Genetic Loci Affecting the Severity of Symptoms of Hirschsprung Disease in Rats Carrying Ednrb.sup.sl Mutations by Quantitative Trait Locus Analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_gale_infotracmisc_A423858996

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracmisc_A423858996

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0122068

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